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Scientific Publications

Lacripep for the Treatment of Primary Sjo ̈gren’s–Associated Ocular Surface Disease: Results of the First-In-Human Study

A synthetic tear protein resolves dry eye through promoting corneal nerve regeneration

Targeting of Heparanase-modified Syndecan-1 by Prosecretory Mitogen Lacritin Requires Conserved CoreGAGAL plus Heparan and Chondroitin Sulfate as a Novel Hybrid Binding Site That Enhances Selectivity

TFOS DEWS II Tear Film Report

Thermally-Responsive Loading and Release of Elastin-Like Polypeptides from Contact Lenses

Lacritin Rescues Stressed Epithelia via Rapid Forkhead BoxO3 (FOXO3)-associated Autophagy That Restores Metabolism

A thermo-responsive protein treatment for dry eyes

Tissue Transglutaminase Is a Negative Regulator of Monomeric Lacritin Bioactivity

Lacritin, a Novel Human Tear Glycoprotein, Promotes Sustained Basal Tearing and Is Well Tolerated

Topical Administration of Lacritin Is a Novel Therapy for Aqueous-Deficient Dry Eye Disease

A Cleavage-potentiated Fragment of Tear Lacritin Is Bactericidal*

Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin

Biosynthesized Multivalent Lacritin Peptides Stimulate Exosome Production in Human Corneal Epithelium

cDNA and Genomic Cloning of Lacritin, a Novel Secretion Enhancing Factor from the Human Lacrimal Gland

Lacritin and other autophagy associated proteins in ocular surface health

Review Lacritin and the tear proteome as natural replacement therapy for dry eye

Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis

The Lacritin-Syndecan-1-Heparanase Axis in Dry Eye Disease

Detection of Prosecretory Mitogen Lacritin in Nonprimate Tears Primarily as a C-Terminal-Like Fragment

Autophagy in the normal and diseased cornea

Lacritin-Induced Secretion of Tear Proteins From Cultured Monkey Lacrimal Acinar Cells