Clinical Trials

Have you been diagnosed with Primary Sjögren’s Syndrome (Primary SS)?

  • Do you suffer from Dry Eye associated with Primary SS?
  • Do you know there is a clinical trial of Lacripep™, an experimental treatment for Dry Eye in patients with Primary SS?
  • The goal of this trial is to restore health to the surface of your eye and treat symptoms of Dry Eye (eye dryness, burning, discomfort) in patients with Primary SS

Interested? Please check out the site nearest you and call the assigned telephone number between 9 am and 5 pm EST (Monday – Friday) or Email us.  Our call in staff based in the US are ready to answer questions and assess whether you likely qualify for the trial. They will then make contact with the clinical site nearest you.

Where are the trial sites? Please scroll down or Google ‘sjogren’s syndrome dry eye‘ on your smart phone.  If you are close to a clinical site, contact information will pop up.    

About the Clinical Trial

  • The study will last 8 weeks and include 5 visits to an ophthalmologist. Patients will be provided with ophthalmic drops of Lacripep™ or placebo. Lacripep™ is a synthetic tear protein fragment of ‘lacritin’. Lacritin and a natural version of Lacripep™ are constituents of normal human tears but are lacking in dry eye tears. In preclinical studies, both restore tearing and eye health. The study purpose is to assess the effectiveness and safety of Lacripep™ in dry eye patients. The trial is FDA approved. It is listed as NCT03226444 in ClinicalTrials.gov.
  • The study is restricted to patients with primary Sjögren’s Syndrome dry eye. It is necessary that you stop your treatment of Restasis or Xiidra two weeks before. Those with punctal plugs inserted two weeks before or later are acceptable. Those on serum tears will need to cease treatment 30 days before.
  • If you think you may qualify (or have patients that qualify) and would be interested in participating in a clinical trial, please see if there is a clinical trial site close to you. The sites are listed below by state.

Questions

Clinical Site Locations

Alabama

The University of Alabama at Birmingham School of Optometry
OcCERF, Ocular Surface Research Institute of the Clinical Eye Research Facility,
121 Henry B. Peters Building, 1716 University Boulevard, Birmingham, AL 35294

       Call 919-353-5938 or Email

California

Global Research Management
1510 South Central Avenue, Suite 300
Glendale, CA  91204

Call 919-943-3054  or Email

Martel Eye Medical Group
11216 Trinity River Drive
Rancho Cordova, CA 95670

Call 919-943-3398 or Email

Milton M. Hom OD, FAAO, FACAAI
1131 East Alosta Avenue
Azusa, CA 91702

Call 919-943-3054 or Email

UC Berkeley Clinical Research Center
381 Minor Hall
UC Berkeley, School of Optometry
Berkeley, CA 94720

Call 919-943-3054 or Email

Wolstan & Goldberg Eye Associates
23600 Telo Ave., Suite 100
Torrance, CA 90505

Call 919-943-3398 or Email

 

Colorado

Corneal Consultants of Colorado
8381 SouthPark Lane
Littleton, CO 80120

Call 919-943-3054 or Email

 

Florida

Bowden Eye & Associates
7205 Bonneval Road
Jacksonville, FL 32256

Call 919-943-3398 or Email

International Eye Associates, PA
1545 Hand Ave., Suite B3
Ormond Beach, FL 32174

Call 919-943-3398 or Email

Perez Eye Center
4506 Wishart Place
Tampa, FL  33603

Call 919-943-3398 or Email

Bruce A. Segal, MD, PA
5258 Linton Blvd, Suite 302
Delray Beach, FL 33484

Call 919-943-3398 or Email

Illinois

Chicago Cornea Consultants, Ltd
1585 N. Barrington Road (Doctors Bldg 2), Building 2, Suite 502
Hoffman Estates, IL 60169 (off the campus of St. Alexius Medical Center)

Call 919-943-3054 or Email

 

Massachusetts

Clinical Eye Research of Boston
955 Main St., Suite 307
Winchester, MA 01890

Call 919-943-3054 or Email

 

Minnesota

Minnesota Eye Consultants, P.A.
10709 Wayzata Blvd
Minnetonka, MN 55305

Call 919-943-3398 or Email

Missouri

Ophthalmology Associates
12990 Manchester Road, Suite 200
St. Louis, MO 63131

Call 919-353-5938 or Email

Tauber Eye Center
4400 Broadway, Suite 202
Kansas City, MO 64111

Call 919-943-3054 or Email

 

North  Dakota

Bergstrom Eye Research
2601 University Drive South
Fargo, ND 58103

Call 919-943-3054 or Email

 

New York

Cornea Consultants of Albany
9 Vista Blvd., Suite 100
Slingerlands, NY 12159

Call 919-353-5938 or Email

 

Ohio

Abrams Eye Center
2322 East 22nd Street, Suite 102
Cleveland, OH 44115

Call 919-353-5938 or Email

Ophthalmic Surgeons & Consultants of Ohio, The Eye Center of Columbus
262 Neil Avenue, Suite 430
Columbus, OH 43215

Call 919-353-5938 or Email

 

Pennsylvania

Scheie Eye Institute
51 N 39th Street
Philadelphia, PA 19104

Call 919-353-5938 or Email

South Dakota

Black Hills Eye Institute
2800 Third Street
Rapid City, SD 57701

Call 919-353-5938 or Email

 

Tennessee

Hamilton Eye Institute, University of Tennessee Health Sciences Center (pending)
930 Madison Avenue #200
Memphis, TN 38103

Call 919-353-5938 or Email

 

Texas

The Eye Clinic of Texas/Houston Eye Associates
1100 Gulf Freeway, Suite 114
League City, TX 77573

Call 919-943-3398 or Email

 

Virginia

Virginia Eye Consultants
241 Corporate Blvd.
Norfolk, VA 23502

Call 919-353-5938 or Email

Vistar Eye Center
3320 Franklin Road
Roanoke, VA 24014

Call 919-353-5938 or Email

 

Still have questions? Please Email our Medical Director, Marc Odrich, MD